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Stem cells: The policy

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By MELISSA LEE / Lincoln Journal Star

Monday, Jun 18, 2007 - 12:14:59 am CDT

These days, it seems the only place you won’t hear folks debating stem cell research is Varner Hall.

Everybody else is doing it. State legislators and academics, Congress and congregations.

But in its East Campus home in the Varner basement, the University of Nebraska Board of Regents remains steadfastly - perhaps strangely - silent on The Big Topic.

Behind the science;

in front of the debate

As stem cell research dominates the headlines with advances in the laboratory and a political standoff in Washington, the Journal Star takes a look at its imprint in Nebraska.

Sunday

THE SCIENCE: Learn about stem cells, the flexible building blocks from which each human being is constructed.

THE RESEARCHER: We’ll introduce you to Dr. Stephen Rennard, a researcher working with embryonic stem cells at the University of Nebraska Medical Center in Omaha.

Monday

THE POLICY: Regents discuss the rules adopted in 2001 that guide research at the University of Nebraska.

Tuesday

THE ETHICS: Supporters and opponents of embryonic stem cell research have the same information. They just don’t agree on an interpretation.

Wednesday

THE BENEFICIARIES: As politicians debate the necessity of embryonic stem cell research, Ben Stahl waits and hopes. Also, where research likely will first be useful.

Thursday

THE POLITICS: Stem cell research likely will play an increasing role at the ballot box. Also, the difference between adult and embryonic stem cells and what the latest scientific discovery means.

Friday

RESEARCHER 2: Meet Dr. Ira Fox, the other UNMC researcher using dated human embryonic stem cell lines to look for cures for liver disease. Also, how the body creates replacement cells.

Sunday

FUTURE OF THE MED CENTER: If UNMC wants a successful future, do its researchers need to study stem cells?



***



UNMC’s policies on stem cells

* Allows adult stem cell research

* Allows embryonic stem cell research in special cases

* Bans cloning

* Says UNMC must follow all federal guidelines regardless of source of research funds, effectively ruling that at least through President George W. Bush’s tenure, UNMC can conduct embryonic stem cell research only on already-existing stem cell lines



***



What regents say

Supporters of embryonic stem cell research

Charles Wilson of Lincoln: “If it’s true that embryos are human beings, then fertility clinics must, must, must be shut down. The opponents, they always ignore that. Ultimately, the opponents are going to have to get honest about addressing this issue. The embryos were going to be destroyed anyway. I double-underline ‘going to be destroyed anyway.’”

Bob Whitehouse of Papillion: “People get it so confused. I’m not for abortion. It’s about giving hope to those who have none.”

Chuck Hassebrook of Lyons: “It won’t cost a single life, but it has the potential to save millions of lives, like from the ravages of Parkinson’s. The right thing to do is to do this research.”

Kent Schroeder of Kearney: “If we curtail this research at the University of Nebraska Medical Center, it will have a chilling effect.”

Opponents of embryonic stem cell research

Jim McClurg of Lincoln: “I don’t believe it’s necessary to destroy human life to do good research. There are many, many good opportunities to do good research within federal guidelines.”

Bob Phares of North Platte: “It’s a destruction of life and that leads me to my opposition. ... I don’t see any evidence that there’s anything particularly strong happening with embryonic stem cell research. I have good friends with Parkinson’s. I empathize. But I also think we have to be guarding the sanctity of life as we’re pursuing good research.”

Randy Ferlic of Omaha: “I’m for stem-cell research but I’m not for obtaining stem cells that require killing an embryo. ... It cheapens our attitude toward our fellow human beings.”

On the fence:

Howard Hawks of Omaha: “Our research programs can succeed without using embryonic stem cells from elective abortions. ... Using leftover stem cells (from fertility treatment clinics), that’s debatable.”

Regents haven’t so much as touched stem cell research since 2001, when they approved guidelines set forth by an ethics committee put together by then-NU President L. Dennis Smith.

And they don’t plan to any time soon, despite the growing political relevance of the topic.

“I’m comfortable with our current policy,” Regent Jim McClurg of Lincoln said.

“Our policy is right for now,” said Regent Chuck Hassebrook of Lyons.

“I don’t think regents need to revisit the policy,” said Regents Chairman Charles Wilson of Lincoln.

What, then, is that policy everyone’s apparently so comfortable with?

The rules are very clear:

Adult stem cell research at the University of Nebraska Medical Center is fine. Embryonic stem cell research is fine, but only in rare cases approved by multiple administrative layers.

Cloning - either type - is not fine.

Finally, UNMC researchers always must abide by federal guidelines, regardless of the source of research funds.

For now, that means UNMC can only conduct embryonic stem cell research on already-existing stem cell lines, because President George W. Bush’s federal policy says no taxpayer dollars will finance the research on new lines. Bush approved 78 cell lines nationwide, two of which are used at UNMC.

It also means that, unlike some other universities, UNMC is not allowed to skirt Bush’s rules by putting private funds toward the controversial research.

Those guidelines were proposed by a 21-member ethics committee that included doctors, scholars, pastors and regular Nebraskans. When the proposal was put before the Board of Regents, just one, Randy Ferlic of Omaha, voted no.

“I was the only regent with a soul,” joked Ferlic, a retired heart surgeon and ardent opponent of embryonic stem cell research.

Now, though, he says he’s OK with the policy, content to wait for someone else to broach what he says is an over-hyped subject before further voicing his opposition.

All seven other regents express similar complacency, no matter their position.

Regents, then, are all but certain to stay mum on the topic at least through Bush’s tenure, because the president has vowed to veto any congressional legislation loosening his restrictions. A newly Democratic Congress is trying to do so but doesn’t have the votes to override Bush.

Depending on whom voters next send to the White House, things could change as soon as 2009.

Should the next president expand embryonic stem cell research, a decision that would filter down to UNMC labs, regents could find themselves deeply divided over the issue.

Half of the current board - Wilson, Hassebrook, Kent Schroeder of Kearney and Bob Whitehouse of Papillion - would support expanding the research. Most of the other half - Ferlic, McClurg and Bob Phares of North Platte - would not.

Howard Hawks of Omaha says UNMC shouldn’t conduct any research related to abortion but that he might be open to using embryonic stem cells left over from fertility treatments.

Still, opponents aren’t prepared to say whether they’d fight looser guidelines.

So, a pending showdown? Maybe. Maybe not.

“It’s all speculation,” Phares said. “To say that we won’t plant our feet and never revisit the issue is silly. We may or may not revisit the issue.”

Of course, the board’s composition isn’t guaranteed to be the same come 2009 because Wilson and Hawks are up for re-election next year. Pro-life candidates have been particularly successful in recent years in securing spots on Nebraska’s decision-making bodies, so embryonic stem cell research opponents may well gain an edge before Bush’s successor takes office.

Then there’s the Legislature, which could enact research-related laws that would surpass regents’ rule.

An all-encompassing cloning ban, for example, was introduced this year, though it never moved out of the Judiciary Committee for debate by the full Legislature. The bill was strongly opposed by several leading UNMC researchers, even though their internal guidelines already prohibit cloning.

The opposition comes because state law is more difficult to overturn than regent guidelines.

Legislators haven’t yet taken up a ban on embryonic stem cell research, but should they ever pass one, regents’ hands would be tied.

That, some say, could cost UNMC millions in grant dollars, reputation points and the loss of prominent researchers. Opponents aren’t convinced UNMC’s future rests on research that has yet to produce tangible successes.

But when the time comes, Whitehouse says, he’s prepared to fight for expansion.

“I hope we can be open to discussion,” he said. “We shouldn’t slam the door. There’s no quick fix to this.”

As he debated whether to run for regent last year, Whitehouse learned a longtime friend and neighbor had been diagnosed with terminal cancer.

She told Whitehouse she could have benefitted from a type of stem cell therapy.

“Bob, do everything you can,” she said shortly before her death.

Whitehouse decided. He would run.

“We cannot turn our backs on research until we find an answer to the suffering people are going through.”

Reach Melissa Lee at 473-2682 or mlee@journalstar.com.


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willie wrote on June 18, 2007 2:41 am:
" This story does nothing but bring forward the argument of religion vs. science. The potential advances made world wide through stem cell research is far more welcome than the "Take 2 aspirin and call me in the morning cause I'm busy reading my Bible" attitude. No wonder Nebraska is on the cutting edge of science. Geeez! "

Confused wrote on June 18, 2007 2:50 am:
" I get nothing out of reading this second segment. All I see being mentioned mostly is UNMC losing out on millions in grant dollars, reputation points and losing researchers because of cloning. I don't want to be cloned. By the time stem cell research is approved, it probably won't do myself any good with a spinal cord injury. 2009 is a long time to have GWB keep saying no to this, but yes lets spend multi billion dollars on a deadly useless war. What are we getting out of that? We have soldiers being killed, loss of limbs, we'll need more money for rehab centers, prosthetics, and durable medical equipment. "

Mike Honcho wrote on June 18, 2007 9:25 am:
" This reads much more like an opinion piece than it does local news. But one poster nailed it...this article will spark a debate of religion vs. science...and he even went ahead and did us the favor of starting that argument himself. I am unclear as to how a person can condone creating life for the sole purpose of destroying it through embryonic stem cell research. I do not condone cloning embryos or harvesting embryos for the sole sake of ESCR. I am neutral in regard to research being performed on embryos produced in fertility clinics that are going to be discarded...so long as the donor receives no monetary compensation. I do believe that life is precious and I don't want to see organizations and universities farming human life. Well Melissa Lee, the ball is in your court...you've gotten one side of the story, let's hear the other. "

eddie wrote on June 18, 2007 11:06 am:
" Most certainly, Nazis and Communists are strong proponents and leaders of "the ends justifies the means" believers. Of course, most believe only some ends justify some means. The same ones also believe they will be the ones to decide when some ends justify some means. Facts and reality be disregarded. "

Not religion wrote on June 18, 2007 4:45 pm:
" Folks, this does not have to be a discussion about religion, although everyone always seems to want to turn it into one. I'm a UNL graduate. Fine institution. I took an advanced logic class there and minored in philosophy. Here's my approach based upon my educational background. Our constitution states that life is an inalienable right for all of us. My biology class taught me that a new human being is made when sperm and egg fuse. This is a new life. A new life in America. A new life that has an inalienable right to life. So, why would it be ethical to create an embryo then destroy it for a few cells? It doesn't matter if this embryo is one second old or nine months old...by our constitution, it has a right to life as a human being. So let's support research that is ethical. Stem cells are being found in amniotic fluid, fat and muscle tissue, bone marrow, cord blood.....all ethical sources with a steadily growing track record of success in disease treatment. Also, be realistic. This is about MONEY and lots of it. Ethics seems to be cast away at times when the promise of a cash cow is made. "

hey life wrote on June 18, 2007 6:33 pm:
" begins when breath begins, read it in the Bible. "

Embryos Will Never Become a Life!! wrote on June 18, 2007 9:07 pm:
" Embryos in a dish have 0% chance of ever becoming a life. How can some people see stem cells as being a human being? There is a third element, a womb, that is needed for an embryo to be considered a life. Testing on embryos needs to be advanced to further research for those suffering from diseases such as diabetes. I know that drug companies will allow a cure to diseases that provide them so much money, and this may be the only chance to find cures. I ask those of you who are opposed to this research...Would you feel the same way if you saw your child suffering from the effects of diabetes? "

Interesting wrote on June 18, 2007 9:13 pm:
" I've always found it interesting that promoters of embryonic stem cell research constantly dismiss adult stem cell research as ever being able to have significant impact on curing diseases. The claim was that only embryonic stem cells have a future in ever being able to make a significant impact and that is what I believed for several years. The funny thing is I keep reading about the advances with adult stem cell research, including adult stem cells being used for paralysis. (Just Google paralysis and Portugal.) "

Intelligentsia wrote on June 18, 2007 11:33 pm:
" Science and religion? How about just plain logic. What is apparent is that one side posits an opinion when human life begins. There are plenty of irreligious people who can look at an embryology textbook and determine that human life begins at conception. Now how about the other side? How about those who favor embryonic stem cell research? Do they posit an opinion as to when human life begins? No. Their position is that we don't know for sure. Logical? One doesn't need religion to see which side is reaching here. "